Prebiotic effect of inulin-type fructans on faecal microbiota and short-chain fatty acids in type 2 diabetes: a randomised controlled trial

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Prebiotic capacity of inulin-type fructans.

The human gut microbiota plays a significant role in human health through its ability to digest food ingredients and manufacture metabolites. This can be positive or negative for host welfare. Moreover, the microflora plays an active role in host defense whereby colonization resistance affords protection against pathogens. Prebiotics are nondigestible food ingredients that target beneficial com...

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Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women.

BACKGROUND & AIMS Inulin-type fructans (ITF) prebiotics promote changes in the composition and activity of the gut microbiota. The aim of this study was to determine variations on fecal short chain fatty acids (SCFA) concentration in obese women treated with ITF and to explore associations between Bifidobacterium species, SCFA and host biological markers of metabolism. METHODS Samples were ob...

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Prebiotic inulin-type fructans induce specific changes in the human gut microbiota

OBJECTIVE Contrary to the long-standing prerequisite of inducing selective (ie, bifidogenic) effects, recent findings suggest that prebiotic interventions lead to ecosystem-wide microbiota shifts. Yet, a comprehensive characterisation of this process is still lacking. Here, we apply 16S rDNA microbiota profiling and matching (gas chromatography mass spectrometry) metabolomics to assess the cons...

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Introducing inulin-type fructans.

Inulin is a generic term to cover all beta(2-->1) linear fructans. Chicory inulin is a linear beta(2-->1) fructan (degree of polymerisation (DP) 2 to 60; DPav=12), its partial enzymatic hydrolysis product is oligofructose (DP 2 to 8; DPav=4), and by applying specific separation technologies a long-chain inulin known as inulin HP (DP 10 to 60; DPav=25) can be produced. Finally, a specific produc...

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Effect of Aerobic Exercise on Blood Pressure of Patients With Type 2 Diabetes: A Randomized Controlled Trial

Background: Hypertension is one of the prevalent and dangerous complications of diabetes mellitus. As it is difficult to control hypertension, the necessity of using new techniques such as non-pharmaceutical methods and complementary therapy increased. This study aimed to determine the effect of aerobic exercise on the blood pressure of patients with type 2 diabetes. Methods: This study was a ...

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ژورنال

عنوان ژورنال: European Journal of Nutrition

سال: 2020

ISSN: 1436-6207,1436-6215

DOI: 10.1007/s00394-020-02282-5